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N-dodecanoyl-L-Homoserine lactone

CAS No. 137173-46-7

N-dodecanoyl-L-Homoserine lactone( C12-HSL )

Catalog No. M26575 CAS No. 137173-46-7

N-dodecanoyl-L-Homoserine lactone is a quorum sensing (QS) signaling molecule, a microbial communication mechanism modulated by acyl homoserine lactone (AHL) molecules impacts biofilm formation in bioreactors.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    N-dodecanoyl-L-Homoserine lactone
  • Note
    Research use only, not for human use.
  • Brief Description
    N-dodecanoyl-L-Homoserine lactone is a quorum sensing (QS) signaling molecule, a microbial communication mechanism modulated by acyl homoserine lactone (AHL) molecules impacts biofilm formation in bioreactors.
  • Description
    N-dodecanoyl-L-Homoserine lactone is a quorum sensing (QS) signaling molecule, a microbial communication mechanism modulated by acyl homoserine lactone (AHL) molecules impacts biofilm formation in bioreactors.(In Vitro):N-dodecanoyl-L-Homoserine lactone inhibits IgE dependent and independent degranulation and mediator release from primary mast cells.
  • In Vitro
    Disruption of cell-cell communication or quorum sensing (QS) is considered a stimulating approach for reducing bacterial pathogenicity and resistance.
  • In Vivo
    ——
  • Synonyms
    C12-HSL
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    137173-46-7
  • Formula Weight
    283.412
  • Molecular Formula
    C16H29NO3
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 25 mg/mL (88.21 mM)
  • SMILES
    CCCCCCCCCCCC(=O)N[C@H]1CCOC1=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Stallmach A, et al. Ferric maltol (ST10): a novel oral iron supplement for the treatment of iron deficiency anemia in inflammatory bowel disease. Expert Opin Pharmacother. 2015;16(18):2859-67.
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